Midazolam

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The drug is used for treatment of acute seizures, moderate to severe insomnia, and for inducing sedation and amnesia before medical procedures. It possesses profoundly potent anxiolytic, amnestic, hypnotic, anticonvulsant, skeletal muscle relaxant, and sedative properties.Midazolam has a fast recovery time and is the most commonly used benzodiazepine as a premedication for sedation; less commonly, it is used for induction and maintenance of anesthesia.

Dosage and routes

• Preoperative sedation
• Adult: IM 0.07-0.08mg/kg 1/2-1hr before anesthesia
• General anesthesia
• Adult: non- medicated patient 0.3-0.35mg/kg over 30 sec, wait 2 min, follow 25% of initial needed; 0.15-0.35 mg/kg over 20-30 sec, 2 min to effect
• Available forms: Inj 1, 5 mg/ml

Side effects

Chills, weakness, tremors, parenthesis insomnia, confusion, and headaches.